Nursing RNC-LRN Questions & Answers

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NCC Low Risk Neonatal Nursing - 2025


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Question: 846


The CRP is 8 mg/L. What does the IgM level indicate, and what infection control measure the nurse enforce?


rmal immunity; continue routine care ute infection; apply contact precautions

mited antibody production; enforce handwashing ternal antibody failure; limit visitation


er: C


nation: Undetectable IgM (<5 mg/dL) is normal, reflecting the infant’s inability to produce dies, increasing hepatitis C risk. Strict handwashing prevents pathogen spread, critical given ure immune system and potential exposure.


ion: 847

year-old G3P2 woman at 38 weeks gestation with a triplet pregnancy delivers via cesarean se fetal distress in Triplet C. Birth weights are Triplet A 2,600 g, Triplet B 2,400 g, and Triple

. Triplet C’s hematocrit is 58%, and blood viscosity is elevated. What neonatal complicatio ikely for Triplet C?


ycythemia

piratory distress syndrome poglycemia

auterine growth restriction

A term infant, now 72 hours old, born to a mother with hepatitis C, weighs 3.3 kg and received no prophylaxis at birth. Labs show a WBC of 15,000/mm³, neutrophils 40%, lymphocytes 50%, and IgM <5 mg/dL.

should


  1. No

  2. Ac

  3. Li

  4. Ma

Answ Expla

antibo the

immat


Quest

A 33- ction

due to t C

1,900 g n is

most l


  1. Pol

  2. Res

  3. Hy

  4. Intr Answer: A

Explanation: In multiple gestations, Triplet C’s low weight (1,900 g) and high hematocrit (58%) suggest polycythemia, possibly from unequal placental sharing. IUGR is present but secondary, while RDS and hypoglycemia are less directly tied to these lab findings.


Question: 848


A term infant, now 48 hours old, born via emergency cesarean, is on nasal cannula at 1 L/min with an

FiO2 of 30%. The infant weighs 3.7 kg, and an ABG shows pH 7.42, PaCO2 36 mmHg, PaO2 68 mmHg, and HCO3 23 mEq/L. The SaO2 is 95%. What should the nurse do?


  1. Switch to CPAP at 5 cm H2O with 30% FiO2

  2. Increase FiO2 to 35%

  3. Maintain current settings

  4. Reduce flow to 0.5 L/min Answer: C

ndicate stability on nasal cannula. Maintaining settings is appropriate. Increasing FiO2 or ing to CPAP is unnecessary, and reducing flow risks hypoxemia.


ion: 849


week neonate with a history of prolonged rupture of membranes develops jittery movements lity on day 2. Serum glucose is 55 mg/dL, calcium is 7.5 mg/dL, and CSF analysis shows 8

/mm³ (90% neutrophils), glucose 20 mg/dL, and protein 150 mg/dL. What is the most likely ying condition mimicking jitteriness?


pocalcemia bdural hematoma poglycemia ningitis


er: D


nation: Jittery movements and irritability with CSF pleocytosis (80 WBCs/mm³), low glucose

), and high protein (150 mg/dL) indicate meningitis, likely from prolonged rupture of memb serum glucose (55 mg/dL) rules out hypoglycemia, mild hypocalcemia (7.5 mg/dL) is unli his alone, and subdural hematoma would not explain the CSF findings.


ion: 850

year-old G3P2 woman at 35 weeks gestation presents with severe epigastric pain, nausea, an

Explanation: Normal pH (7.42), PaCO2 (36 mmHg), and adequate oxygenation (PaO2 68 mmHg, SaO2 95%) i

switch


Quest


A 35- and

irritabi 0

WBCs

underl


  1. Hy

  2. Su

  3. Hy

  4. Me


Answ


Expla (20

mg/dL ranes.

Normal kely to

cause t


Quest

A 34- d a

blood pressure of 165/105 mmHg. Laboratory results show a platelet count of 85,000/mm³, AST 220 U/L, ALT 250 U/L, and LDH 950 U/L. The neonate is delivered emergently via cesarean section with an umbilical artery pH of 7.16, PCO2 60 mmHg, and base deficit -13 mEq/L. What maternal condition most likely contributed to the neonatal acidosis?


  1. Placental abruption

  2. HELLP syndrome

  3. Chorioamnionitis

  4. Cord prolapse

Answer: B


Explanation: The maternal symptoms (epigastric pain, hypertension) and labs (thrombocytopenia, elevated liver enzymes, high LDH) indicate HELLP syndrome, a severe preeclampsia variant. This condition causes placental insufficiency, leading to fetal hypoxia and acidosis (pH 7.16, base deficit -13 mEq/L). Placental abruption involves bleeding, chorioamnionitis requires infection signs, and cord prolapse causes variable decelerations, not this pattern.


Question: 851


year-old mother delivered a term infant 6 days ago and is taking fluoxetine 20 mg daily for rtum depression. The infant is exclusively breastfed, gaining 25 g/day, but exhibits irritabilit leep. Fluoxetine levels in breast milk are 50 ng/mL (therapeutic range: 20–100). What is the

edication effect on this infant?


strointestinal irritation from fluoxetine duced milk quality from maternal depression ug withdrawal from inconsistent exposure

otonin excess causing neurobehavioral changes er: D

nation: Irritability and poor sleep with fluoxetine levels of 50 ng/mL suggest serotonin excess ia breast milk, a known side effect of SSRIs. Milk quality, withdrawal, and GI irritation are

tent with the infant’s normal weight gain and exposure pattern.


ion: 852


week gestation male neonate, now 3 days old, is noted to have a reducible mass in the left in uring a bath. The neonate is asymptomatic, feeding well, and has normal bowel movements ost appropriate management for this inguinal hernia?


ergent surgical repair

servation for spontaneous resolution ctive repair within 1-2 months

A 34-

postpa y and

poor s most

likely m


  1. Ga

  2. Re

  3. Dr

  4. Ser Answ

Expla in the

infant v less

consis


Quest


A 38- guinal

canal d . What

is the m


  1. Em

  2. Ob

  3. Ele

  4. Manual reduction and truss application Answer: C

Explanation: A reducible inguinal hernia in an asymptomatic neonate does not require emergent surgery but should be repaired electively within 1-2 months to prevent incarceration, a risk due to the patent processus vaginalis. Observation alone is insufficient, and trusses are not standard care. Timing balances risk and surgical readiness.


Question: 853

A 34-week preterm neonate presents with short limbs, a large head with frontal bossing, and a narrow thorax on X-ray. The neonate develops respiratory distress, and skeletal survey confirms rhizomelic shortening and metaphyseal flaring. Genetic testing reveals an FGFR3 mutation. What is the most likely diagnosis and its inheritance pattern?


  1. Cystic fibrosis with autosomal recessive inheritance

  2. Trisomy 21 with nondisjunction

  3. Achondroplasia with autosomal dominant inheritance

    er: C


    nation: The short limbs, large head, narrow thorax, and FGFR3 mutation confirm achondropl osomal dominant skeletal dysplasia, often a new mutation. Trisomy 21 lacks skeletal finding ibrosis affects lungs and pancreas, and DiGeorge involves 22q11.2 deletion, not FGFR3.


    ion: 854

    nate is delivered at 43 weeks gestation with a birth weight of 3,400 g (25th percentile), lengt 0th percentile), and head circumference of 36 cm (50th percentile). Physical exam shows dry skin, long nails, and meconium staining. The neonate develops seizures at 12 hours. What

    ikely classification and complication?


    -term with perinatal asphyxia m with hypoglycemia

    preterm with respiratory distress term with hypothermia


    er: A

    nation: At 43 weeks with post-term features (cracked skin, long nails) and AGA measuremen is post-term. Seizures suggest perinatal asphyxia, a risk from placental dysfunction. Other do not align with gestation or symptoms.


    ion: 855

    DiGeorge syndrome with microdeletion Answ

Expla asia,

an aut s,

cystic f


Quest

A neo h of 52

cm (5

cracked is the

most l


  1. Post

  2. Ter

  3. Late

  4. Pre


Answ

Expla ts, the

neonate options


Quest


A term infant, now 72 hours old, presents with lethargy and a glucose of 28 mg/dL (normal: >50). The infant weighs 3.5 kg, and the nurse starts D10W at 80 mL/kg/day via a peripheral IV. A metabolic panel shows sodium 134 mEq/L (normal: 135–145) and calcium 7.8 mg/dL (normal: 8.5–10.5). What should the nurse prioritize?


  1. Monitor urine output for fluid balance

  2. Increase dextrose to 12.5% in the IV fluid

  3. Administer calcium gluconate 100 mg/kg IV

  4. Request a sodium bolus to correct hyponatremia

Answer: C


Explanation: Hypocalcemia (7.8 mg/dL) with severe hypoglycemia (28 mg/dL) and lethargy requires urgent calcium correction to prevent complications like seizures. Glucose is addressed, urine monitoring is secondary, and mild hyponatremia (134 mEq/L) doesn’t need a bolus.


Question: 856


term with apnea

preterm with hypocalcemia m with polycythemia

-term with jaundice


er: B

nation: At 36 weeks with AGA measurements (50th percentile) and late preterm features (sof onate is late preterm. Hypocalcemia (7.0 mg/dL) causes jitteriness, a common issue in late p due to immature parathyroid function. Other options mismatch gestation or findings.


ion: 857


infant, now 6 days old, is receiving morphine 0.1 mg/kg/dose IV every 4 hours for postope fter a pyloromyotomy. The infant weighs 3.8 kg, and the NIPS score is 4 (moderate pain) de oses. A blood level is 25 ng/mL (therapeutic: 10–40 ng/mL). What pharmacological interve the nurse consider?


acetaminophen as an adjunct

rease the dose to 0.15 mg/kg for better control itch to fentanyl for faster onset

duce the interval to every 3 hours


er: A

A neonate born at 36 weeks gestation weighs 2,500 g (50th percentile), with a length of 46 cm (50th percentile) and head circumference of 32 cm (50th percentile). Physical exam shows soft ears, minimal lanugo, and a calcium level of 7.0 mg/dL at 24 hours with jitteriness. What is the most likely classification and complication?


  1. Pre

  2. Late

  3. Ter

  4. Post


Answ

Expla t ears),

the ne reterm

infants


Quest


A term rative

pain a spite

three d ntion

should


  1. Add

  2. Inc

  3. Sw

  4. Re


Answ


Explanation: A NIPS score of 4 with a therapeutic level (25 ng/mL) suggests inadequate pain control. Adding acetaminophen enhances analgesia without escalating opioid risks. Increasing dose or frequency risks toxicity, and switching to fentanyl is unnecessary with morphine’s efficacy.


Question: 858

A 36-week gestation male neonate, now 7 days old, has a urine output of 0.6 mL/kg/hour and a serum sodium of 150 mEq/L. The neonate is on formula feeds and has no edema. Ultrasound shows normal kidneys. What is the most likely cause of this renal function alteration?

  1. Diabetes insipidus

  2. Dehydration

  3. Syndrome of inappropriate ADH

  4. Renal tubular acidosis Answer: B


ion: 859


nurse assesses the gag reflex in a 2-day-old neonate with a PaCO2 of 55 mmHg and HCO3 of 2 The reflex is present but weak. What is the most likely cause?


nial nerve damage

rmal variation in reflex strength tabolic alkalosis enhancing the reflex spiratory acidosis weakening the reflex


er: D


nation: PaCO2 55 mmHg and HCO3 28 mEq/L indicate respiratory acidosis with partial nsation, which can cause lethargy and weaken reflexes like the gag. Option B is incorrect as ag is not typical.


ion: 860


erm infant born at 35 weeks gestation, now 5 days old, is receiving sucrose 24% orally for p a venous puncture. The infant’s heart rate is 165 bpm (baseline 140), and the N-PASS scor ain). What nonpharmacological intervention should the nurse add?


rease ambient light for distraction

Explanation: Low urine output with hypernatremia and normal kidneys suggest dehydration, likely from inadequate fluid intake or losses, common in preterms transitioning to feeds. Diabetes insipidus causes dilute urine, SIADH causes hyponatremia, and renal tubular acidosis involves acidosis, none aligning with this presentation.


Quest

A 8

mEq/L.


  1. Cra

  2. No

  3. Me

  4. Re

Answ Expla

compe a

weak g


Quest


A pret ain

during e is 3

(mild p


  1. Inc

  2. Apply a cold pack to the site

  3. Swaddle the infant during the procedure

  4. Delay the puncture for 30 minutes Answer: C

Explanation: A score of 3 with tachycardia (165 bpm) indicates mild pain despite sucrose. Swaddling enhances comfort and reduces stress, complementing sucrose. Cold packs numb but don’t soothe, light increases distress, and delay doesn’t address immediate pain.

Question: 861

A 38-week gestation male neonate, now 3 days old, undergoes circumcision with a Plastibell device. On day 7, the parents note the ring has not fallen off, and the penis is swollen with a grayish discoloration. What is the most likely postoperative complication requiring intervention?


  1. Retained Plastibell ring

  2. Necrosis from tight ring

  3. Wound infection

    er: B


    nation: Delayed ring detachment with swelling and grayish discoloration suggest necrosis fro lastibell ring compromising blood flow, requiring urgent removal. Infection involves fever, d ring alone doesn’t cause discoloration, and adhesions form later, none matching this ische


    ion: 862


    week preterm neonate presents with holoprosencephaly, polydactyly, and a midline facial cle type analysis shows 47,XY,+13, and the neonate develops apnea requiring ventilation. What ppropriate family counseling point regarding recurrence risk?


    gh risk due to autosomal recessive inheritance currence risk is low due to sporadic nondisjunction derate risk due to parental translocation

    risk as it’s a de novo mutation er: B

    nation: The features (holoprosencephaly, polydactyly, midline cleft) and karyotype 47,XY,+1 confirm Trisomy 13, typically a sporadic nondisjunction event with low recurrence risk (<1%) unl al translocation is identified (not suggested here). Recessive inheritance and de novo mutatio

    aracterize this condition.

    Adhesion formation Answ

Expla m a

tight P

retaine mic

picture.


Quest


A 34- ft.

Karyo is the

most a


  1. Hi

  2. Re

  3. Mo

  4. No


Answ

Expla 3

ess a

parent n

misch


Question: 863


During a neurological exam, a nurse strokes the sole of a 3-day-old neonate’s foot from heel to toe in an inverted “J” pattern. The big toe dorsiflexes, and the other toes fan outward bilaterally. The neonate’s serum ionized calcium is 4.0 mg/dL (normal: 4.4-5.2 mg/dL), and magnesium is 1.8 mg/dL. How should the nurse interpret this Babinski reflex finding?


  1. Abnormal response indicating upper motor neuron dysfunction

  2. Hypocalcemia-induced exaggeration of the reflex

  3. Normal finding for a neonate of this age

  4. Potential spinal cord injury requiring imaging Answer: C

Explanation: A positive Babinski reflex (dorsiflexion of the big toe with fanning of others) is normal in neonates up to 12-24 months due to immature corticospinal tracts. The slightly low ionized calcium (4.0 mg/dL) may cause neuromuscular irritability, but it does not alter the Babinski reflex’s expected presence in a 3-day-old.



year-old mother delivered a term infant 6 days ago and is supplementing breastfeeding with formula due to perceived low supply. The infant’s weight gain is 25 g/day, and the mother asks ab

sition of formula compared to breast milk. Lab results show infant iron at 55 µg/dL (normal hat should the nurse explain?


mula lacks antibodies found in breast milk mula has higher iron to prevent anemia mula contains more fat than breast milk mula is lower in carbohydrates


er: B


nation: Low iron (55 µg/dL) and normal weight gain (25 g/day) highlight a nutritional gap. F fied with higher iron than breast milk to prevent anemia, a key compositional difference. odies, fat, and carbs vary, but iron is most relevant here.


ion: 865

year-old G1P0 woman at 39 weeks gestation undergoes a cord gas analysis at delivery due to ged second stage labor. The umbilical artery pH is 7.10, PCO2 is 60 mmHg, and base defici The neonate’s Apgar scores are 5 at 1 minute and 7 at 5 minutes. What is the most likely

al complication?


ebral palsy

poxic-ischemic encephalopathy

Question: 864


A 33-


out the

compo : 60–

170). W


  1. For

  2. For

  3. For

  4. For Answ

Expla ormula

is forti Antib


Quest

A 28-

prolon t is -15

mEq/L. neonat


  1. Cer

  2. Hy

  3. Respiratory distress syndrome

  4. Seizures Answer: B

Explanation: Severe acidosis (pH 7.10, base deficit -15 mEq/L) and low Apgar scores indicate perinatal asphyxia, increasing the risk of hypoxic-ischemic encephalopathy. Cerebral palsy is a long-term outcome, not an immediate complication. Respiratory distress and seizures may occur but are secondary to HIE.

Question: 866


A term infant, now 72 hours old, is being treated for suspected neonatal sepsis with intravenous gentamicin. The ordered dose is 4 mg/kg every 24 hours, and the infant weighs 3.2 kg. The nurse administers 12.8 mg at 0800, but a trough level drawn at 0700 the next day is 2.5 µg/mL (therapeutic: 0.5–2 µg/mL; toxic: >2 µg/mL). What pharmacokinetic principle should guide the nurse’s next action?


  1. Hold the next dose and notify the provider

  2. Adjust the dose downward due to reduced clearance

  3. Increase the dosing interval to 36 hours


    er: A


    nation: A trough level of 2.5 µg/mL exceeds the therapeutic range, indicating accumulation d ure renal clearance in a 72-hour-old infant. Holding the dose and notifying the provider prev y, aligning with pharmacokinetic monitoring of blood drug levels. Adjusting without consult

    intervals arbitrarily, or continuing risks harm.


    ion: 867


    neonate born to a mother with a history of unexplained stillbirth presents on day 4 with pal ocrit of 30%, hemoglobin of 10 g/dL, reticulocyte count of 12%, and total bilirubin of 16 mg

    0.6 mg/dL). DAT is negative. What is the most likely underlying condition?


    al-maternal hemorrhage ysiologic anemia editary spherocytosis kle cell disease


    er: A


    nation: The pallor, anemia (hematocrit 30%, hemoglobin 10 g/dL), high reticulocyte count (1 conjugated hyperbilirubinemia (15.4 mg/dL) with a negative DAT and maternal history of th suggest fetal-maternal hemorrhage causing acute blood loss. Hereditary spherocytosis wo ave a positive DAT or spherocytes, physiologic anemia occurs later, and sickle cell disease

    Continue the current regimen and recheck in 24 hours Answ

Expla ue to

immat ents

toxicit ation,

altering


Quest


A term lor,

hemat /dL

(direct


  1. Fet

  2. Ph

  3. Her

  4. Sic Answ

Expla 2%),

and un

stillbir uld

likely h would

show HbSS on screening.


Question: 868


A 34-week preterm infant, now 10 days old, has a serum calcium of 6.3 mg/dL, phosphorus of 8.8 mg/dL, and alkaline phosphatase of 480 U/L. The infant is on TPN with minimal enteral feeds. What is a potential consequence if this condition persists?


  1. Pathologic fractures

  2. Cataracts

  3. Adrenal insufficiency

  4. Hepatomegaly Answer: A

Explanation: The infant’s hypocalcemia (6.3 mg/dL), hyperphosphatemia (8.8 mg/dL), and elevated alkaline phosphatase (480 U/L) indicate metabolic bone disease of prematurity. If untreated, poor bone mineralization can lead to pathologic fractures, a significant consequence in preterm infants with prolonged TPN use.


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